Product Related Literature

Pancreatic adenocarcinoma is a malignant tumor derived from a cell transformed has been made in pancreatic tissue. Generated in the exocrine pancreas component, the most common type of pancreatic cancer, which accounts for 95% of these tumors are (tumors showing a glandular architecture light microscopy) adenocarcinoma. The event is raised by the pancreatic islet cells, a small percentage can be classified as neuroendocrine tumors. Signs and symptoms, location of the tumor tissue Finally, based on the type and size, lead to diagnostics and can include jaundice abdominal pain, and back pain.

Pancreatic cancer is the most common cause of Fourth of cancer-related death in the United States and around the world eight. There is a very poor prognosis pancreatic cancer: all stages, total 1 – respectively, 5-year relative survival rate of 6% and 25%, local failure of the 5-year survival rate is the median survival for locally advanced , shows more than 80% of people together to be about 15%, in metastatic disease, is about 10 6 months. However, people are different – some, they are diagnosed only if they are terminally ill already, therefore, we have a few weeks or a few days. Even if you do not work, others will be able to have a slow progression, to live several years. Men, women and more the possibility of more than 30% higher in pancreatic cancer. Possibility of human origin and nationality of Africa will develop pancreatic cancer than white people is high.

It is debatable whether a risk factor for pancreatic cancer alcohol consumption. In general, the association constant is low, most of the research does not allow what the relationship. Compared chronic pancreatitis, and other types, in turn, often predisposition cancer associated with alcohol consumption, pancreatic cancer, chronic pancreatitis, the main cause too much alcohol chronic pancreatitis is not a precursor of pancreatic cancer . In some studies, the relationship between risk is shown to increase with alcohol intake. On the order of drink four or more, risk is the highest in heavy drinking per day in particular. Because it can not be a risk factor of “cancer, may make it to the alcohol level, it is an increased risk for people who consume alcohol to 30 grams per day about two spirits / day more and more people “The analysis pooled, concluded:” pancreas that there is no is not known. Our findings, risk of cancer of the pancreas and the consumption of 30 g or more alcohol per day is one and a slight increase in research or. “Some that I will warn that the findings of them, and there is a possibility of confounding factor is the cause. Even if there is a link, “may be due to the content of alcoholic drinks some” other than alcohol itself,. It was found that the risk is low to drink white wine in the Dutch study.

The majority of jaundice patient pain experience of pancreatic cancer, or weight loss,. Pain is present in 85% of 80% to patients with metastatic disease or advanced locally advanced. Typically, pain is felt in the dull pain and abdominal radiation on a cross back. Well, it is exacerbated by eating even intermittent. it is possible to weight loss is deep, it may be associated with anorexia, early satiety, diarrhea and steatorrhea. In most cases, jaundice is accompanied by itching and dark urine. Jaundice painful is present operable to be present in approximately half of painless jaundice patients and disease unresectable locally, in about half of patients with curable lesions potentially.

Initial performance may be dependent on the location of the cancer. Those of the head of the gland cancer and or tail usually present pancreas body is present steatorrhea, weight loss, jaundice in generally in weight loss and pain. Atypical diabetes, it is recent, but the recent emergence of the attack in front of pancreatitis history of thrombophlebitis or unexplained (Trousseau sign), has been pointed out frequently. Courvoisier is able to determine the gallbladder was painless jaundice extension showing strongly pancreatic cancer exists, signatures, and using the differentiation of pancreatic cancer by gallstones. Fatigue eat the pain, difficulty and irritability are also present. In most cases, pancreatic cancer was discovered during the evaluation of the above symptoms.

The liver function tests, may combination of results showing (raised level conjugated bilirubin, γ-guru Tamil transferase, of alkaline phosphatase) bile duct obstruction is displayed. The (carbohydrate antigen 19.9), in many cases, is a tumor marker that is increased in pancreatic cancer CA19-9. However, I lack the sensitivity and specificity. If you turn off on top of the 37 that have been using the U / ml, this marker, you will have a specificity of 87% in benign sophisticated from malignant disease and sensitivity of 77%. CA 19-9 can be can be normal at the beginning of course, increase as a cause of benign biliary obstruction. For example, an imaging test computer tomography and endoscopic ultrasound (CT), such as (EUS) may be used to identify the position and shape of cancer. Definitive diagnosis is made by surgical removal of tissue suspected radiological or endoscopic needle biopsy. In many cases, endoscopic ultrasound is used to guide the needle biopsy procedure visually. However, in general, pancreas, is arranged by using a scanner. In fact, histological diagnosis is not required to serve for determining ablation histological analysis and tumor should begin chemotherapy.