|Product name||Ovary granulosa cell tumor|
|No. of samples||1|
|Description||eovary, granulosa cell tumor
Age/Sex : 48/F
Product Related Literature
Ovary granulosa cell tumor is a tumor arising from the granulosa cells granulosa cell tumor. These tumors are non-epithelial tumor Sex cord stromal tumors by a group, and gonad. Usually, granulosa cells are found only in the ovary but granule cell tumor was discovered in ovary (see testicular cancer and ovary) testis. Considered malignant tumors, these tumors can be treated in the same way as other cancers of the ovary is. When you stage a system for these tumors, to be the same as in most cases of epithelial tumors, peak age presence they occur as step I. is 50-55 years old, they can occur at any age There is likely to be. Similar immature granulocyte tumor cells, is a rare tumor but different. I also occurs in the testes and ovaries. In the testis, it is very rare, it malignant.Reported adult has been reported it. It also might occur in other tissues such as the breast, but the transition Krukenberg tumor, ovarian cancer, primary site, refers to the digestive tract classic. Gastric adenocarcinoma of the pylorus, is the most common source in particular. Depending on the (80%) metastatic often Krukenberg tumors, has been found in the ovary. With an average age of 45 years, Krukenberg tumors can be seen in all age groups. In most countries, cancer that has spread to the ovary is about 1-2% of ovarian cancer. Remain in the ovary, it is a primary site of cancer. However, they represent a large percentage (about 20%) much of ovarian cancer due to increased proliferation of gastric cancer in Japan. It is metastasis following accounts for about 15% of metastatic tumors appear Krukenberg tumor as has occurred in the ovaries first, resulting from germ cells and epithelial ovarian tumors so. a person who has a malignant tumor nongynecologic, about 20% of the adnexal mass is malignant, 60% is a Krukenberg tumor.
Often, Krukenberg tumors come to the attention of when they cause pain and pelvic pain during intercourse abdomen, bloating, or ascites,. Causes changes in virilization and hirsutism and menstrual pattern, vaginal bleeding as a major sometimes symptoms, in the production of hormones, the result can cause the reaction of ovarian stroma Krukenberg tumor. All of these symptoms, is a non-specific, there is a possibility that a variety of problems other than cancer, on the Source, the confirmatory test, such as ovarian and CT scan laparotomy or diagnosis be made at only after the biopsy I can.
The exact mechanism Discussion of metastasis of tumor cells other stomach, ovarian or colon. It was believed a classic, and it is considered the seeding, more likely more spread through the lymphatic vessels in the spread of consideration abdominal tumor directly. Average age at diagnosis of Krukenberg tumor month is associated with an increased ovarian blood supply relatively part. Microscopically, the Krukenberg tumor, is characterized by a seal ring that secrete mucin in tissue cells of ovarian primary tumor is detected often, seal ring the same cells found normally. However, there is a possibility that the fine features of the other win. Gastric cancer, especially breast cancer adenocarcinoma, and breast cancer,, Krukenberg tumor is a metastasis of the most common invasive lobular carcinoma in particular, but can occur in addition, large intestine, small intestine, large intestine, gall bladder, gall bladder or urinary bladder, bile duct , ampoule pancreas, cervix or of Vater.
Immunohistochemistry may be useful in the diagnosis of Krukenberg tumor from primary ovarian tumor, but should be used with caution. For example, could be a thing of the colon derived might be high tumor is negative and immunoreactive (CK20) and cytokeratin 20 for CEA (CK7) cytokeratin 7. For (metastatic) is a secondary Krukenberg tumor, you can manage to manage through the identification and treatment of the primary cancer in a rational manner. Optimal treatment of Krukenberg tumor is unknown. The role of surgical resection is not enough, but if the transition is confined to the ovary, there is a potential to improve the survival rate of surgery. The role of chemotherapy and / or radiation therapy is unclear, but it may be beneficial at times.