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In mammals, it is endocrine gland, which is located on top of the kidneys adrenal glands (also known as adrenal glands) in humans, but the shape of the right adrenal gland was a triangle, left adrenal gland is a half-moon shape. Through the synthesis of catecholamines, such as norepinephrine and (adrenaline) epinephrine such, in response to stress, is responsible mainly for the release of hormones and corticosteroids, such as cortisol such they. I produce androgen in cortical layer on the inside of you also, endocrine glands of these. Adrenal, affect kidney function through the secretion of aldosterone, the recent data, the adrenal, adrenal cortex cells, suggesting that shown in neuroendocrine characteristics under physiological conditions and pathological, this nerve endocrine differentiation appears to be limited to the cells of the zona, the regulation of adrenal function may be important for secretion.

Located quadrilaterial shape excellent retroperitoneum kidney, adrenal glands, are arranged on both sides. The total weight of the adrenal gland are surrounded by the renal fascia and fat capsule in 7-10 grams.They adult range. Each adrenal gland has two structures of production either, the brain and the inner adrenal medulla outside the hormone. Cortex to produce cortisol, aldosterone and androgens mainly, the brain generates a norepinephrine and epinephrine mainly. Unlike the direct control of the brain cortex, renin and hormone, secreted by the pituitary gland under the control of neuroendocrine hypothalamus – is regulated by the angiotensin system.

Adrenal cortex is devoted to the production of androgen hormones and corticosteroids. Skin cells specific produce, and certain hormones, including androgens aldosterone and cortisol, and androstenedione. Under normal conditions, adrenal unload, human produce the equivalent of 35-40 mg per day cortisone acetate. Adrenal cortex is composed of a layer or three zones. The anatomical band may be understood in microscopic level that can each zone is identified based on anatomical characteristics and structural and distinguish from one another. Not only the adrenal cortex, showing a zonation functional: based on the specific enzymes that are present within each zone, the zone will produce and secrete another hormone.

By (known as CYP11B2 also) aldosterone, enzyme aldosterone system, the outermost layer of the spherical zone, is a major center for the production of mineralocorticoid. Aldosterone is responsible mainly for the stabilization of long-term blood pressure. Distal tubule, it aldosterone effect in the collecting duct of the kidney, which causes an increase reabsorption of increased release of both (from the collection intercalated cells channel) hydrogen ion and potassium and sodium (from basic cell). Sodium retention in response to the distal colon, and I stimulate the sweat glands of the aldosterone receptor. Calcium influx requires certain through sustainable production of aldosterone, a Ca2 channel low-voltage activation, but zona cells isolated were recorded too is hyperpolarization In order to enable the entry channel of Ca2 at a voltage of film, I will be considered as nonexcitable. However, to generate a membrane potential oscillations of low frequency spontaneous mouse zona cells in the adrenal gland slice, this natural electrical excitability of the zona glomerulosa cells, angiotensin II provides a platform for the production of Ca2 of repeatedly potassium and aldosterone production two major regulator channel signal can be controlled by the cell. Angiotensin II is derived from the converted plasma angiotensin I of angiotensinogen by renin production from the juxtaglomerular cells of the kidney.

Expression of neuron-specific proteins in the zona glomerulosa cells that have been reported by several authors human cortical tissue prediction, expression of protein neural cell adhesion molecule in glomerulosa cell of the reflection function of regenerative cells such as (NCAM) It will lose NCAM immunoreactivity after who suggest that has moved to the bundle-shaped zone. However, along with other data, NCAM expression may reflect the neuroendocrine differentiation of these cells neuroendocrine functions glomerulosa cell.