Product name | Esophagus basaloid |
Cat. No. | 6281233A |
No. of samples | 1 |
Description | esophagus, basaloid Age/Sex : 58/M |
Price | 197 EUR |
260 USD | |
170 GBP |
Product Related Literature
Esophagus basaloid carcinoma is a variant of a rare lung cancer tissue containing cells showing a functional and cytological organizational structure of basal cell carcinoma and squamous cell lung cancer. Lung cancer is a heterogeneous family and very large malignant tumor. Histological variation of more than 50 of lung cancer has been recognized in the fourth edition of the classification of the World Health Organization explicit lung tumor. Many of these individuals, is very rare, it has been described recently in there, you will continue to be fully understood.
Basal cell form of lung cancer have been described in peer-reviewed medical literature by her colleague Dr. Elizabeth Villa Blanc in 1992 first. The revision of the third classification system, which was announced lung tumor typing of the World Health Organization, in 1999, variants of the basal cell of both lung large cell carcinoma and squamous cell lung cancer, is recognized as an individual. And in the revision of the fourth shallow SqCC is classified as one of the variants of four recognition of squamous cell carcinoma of the lung (world standard now) system. The embodiment of SqCC, I have considered the non-small cell lung cancer.
I considered the true incidence of squamous cell lung carcinoma and basal cell incidence is unknown, but this type of lung cancer to be relatively common. One of the main research of this embodiment, Moro · Sibilot We have found prevalence of 6.3% of shallow SqCC in consecutive patients of 1418 and in NSCLC institution. Is associated with smoking strongly – such as variants of the recognition of virtually all of lung cancer – basaloid lung cancer. Basaloid architecture in lung cancer is the connection of tobacco exposure strongest than the major cell type of any other NSCLC that the smokers having squamous cell carcinoma exposure and severe, are particularly popular is shown.
In comparison with other forms of lung cancer, often shallow SqCC occurs assumed slightly larger than the average. SqCC also to be related to the introduction of a later age a little, meaning / effect the true size of basaloid age interaction is unknown. Usually, near bronchial for most, basal cell squamous cell carcinoma begins in the middle. Primary basal cell carcinoma of the lung occurs, there is a form of multi-center.
After examining the tumor samples with cells and tissues of malignant viable under an optical microscope, and then identified the particular characteristics of the several pathologists, like lung cancer were diagnosed eventually with other forms of shallow SqCC . In the case of shallow SqCC, that the data for the differentiation of squamous cell (ie, the generation bridge between cells, keratin, the tonofilament packet) and, to identify both of basaloid architecture make appropriate diagosis is essential . High molecular weight keratin positive and P63, and immunohistochemical markers can be mentioned the lack of expression of thyroid transcription factor-1 and suggest that it is useful in making an accurate diagnosis of superficial SqCC them. Of the other lung cancer, the main differential diagnosis in the case of shallow SqCC doubt, contains a high neuroendocrine cancers such as large cell neuroendocrine carcinoma and small cell carcinoma, such as this. The pathologist problem differential diagnosis is particularly acute when it is necessary to use a cytology sample or a biopsy of the small quantity. It is also possible to distinguish basal cell variants SqCC other poorly differentiated squamous cell carcinoma is difficult.
Squamous cell carcinoma and basal cell, to be due to pre-malignant lesions of dysplasia in the airways of the lung are shown, we may suffer genetic damage additional leading to progression of sit squamous and basal cell carcinoma cells in the field of severe dysplasia Following the exposure continue the stimulation of carcinogenic and other cigarette smoke. CIS is a malignant lesion completely, but by definition, cancer cells do not invade the outside organization to distinguish the original site of Genesis still.
As with other forms of almost all of NSCLC, prognosis of basaloid squamous cell carcinoma is very bad. The case number, powerful statistical, and data of many (if not all), basal cell squamous cell carcinoma of the lung, that the “traditional” (ie, likely to have a poor prognosis more shows, tend to be to a study published and, quite small no. basal cell) squamous cell carcinoma of the lung. Likely to be generated in the natural history of tumor compared these distant metastases previously is due to decreased survival (i.e., II and Stage I) deteriorated embodiment basal cell tumors at an early stage survival rate as NSCLCs and squamous cell carcinoma of the other pointed out common.
The decades of the end of the 20th century, histological variants of all of NSCLC were treated equally in general. 10 years, in different embodiments of malignant tumors, which show a clinical genetic characteristics, and biological variety, including the response to treatment is generally revealed it. As tend to be excluded from the clinical trials, the most effective treatment for basal cell carcinoma, squamous cell carcinoma, frequent fluctuations lung cancer, including tumors consisting of a mixture of histological subtype, (s) it remains unknown. In general, these options appear to be processed according to standard protocols in place for squamous cell carcinoma.