|Product name||Uterine cervix carcinoma|
|No. of samples||1|
|Description||uterine cervix carcinoma
Age/Sex : 54/F
Product Related Literature
It is possible sometimes, for example, occur in other parts of the body such as the neck is small cell carcinoma (also known as a “cancer cell oats” or “small-cell lung cancer”), it is often most highly malignant uterine cancer is a type of cancer that occur in the lung, prostate, and gastrointesinal tract. If it is associated with the lung is called due to the cytoplasm and scarce flat cells sometimes as “oat cell carcinoma”.
I This is believed to be derived from neuroendocrine cells in Feyrter cells called bronchi. Therefore, they express the neuroendocrine marker variety, it can lead to ectopic production of hormones such as ACTH, potential and ADH lead to Cushing’s syndrome and paraneoplastic syndromes such. About half of all people diagnosed with Lambert-Eaton myasthenic syndrome, which has a small cell lung cancer probably be found.
Metastatic non-small cell cancer (and therefore arranged in a different way) is widely quick and most often small cell carcinoma of the lung. There is involvement of mediastinal lymph nodes and usually hilar. The SCLC, may occur in a wide variety of combinations of histologic variants of other lung tissue containing complex malignant impurities very. If it is found in the form of a separate one or more adenocarcinoma and squamous cell carcinoma, and lung such as to diagnose malignant tumors, and was then classified in a mixed small cell lung cancer. Of SCLC, C non-small cell lung cancer, a subtype that is currently recognized.
Synthesis SCLC is the current position, and are treated in the same manner as “clean” small-cell lung cancer, but recent studies have shown, the operation is able to improve performance in the early stages of this type of tumor . Smoking is a major etiologic agent. Are as lung cancer and other symptoms. In addition, by the cell neuroendocrine origin of them, small cell carcinoma, and release substances that cause paraneoplastic syndromes such as Lambert-Eaton myasthenic syndrome such often.
The main venue of small cell carcinoma, it is not a very rare outside of the pleural cavity and lung, it is called (EPSCC) small cell lung cancer. Outside of the respiratory tract, small cell carcinoma, can occur in the bladder cervix, prostate, liver, pancreas, or gastrointestinal tract,. Thought to consider a new case 1,000 per year in the United States that is histologically similar small cell lung cancer, the treatment of small cell lung cancer, it is used to treat EPSCC typically. Line initial therapy in general with etoposide and cisplatin. In Japan, the first-line treatment, transition to cisplatin and irinotecan. Main spot of the skin when a Merkel cell carcinoma more.
Small cell lung cancer is divided into two phases comprising stage a limited clinical pathological long and rich stage . Tumors is shown only from the chest generally by step, whether or not it is that can be incorporated into the portal radiotherapy single total weight of the breast tumors practice is determined by the presence or absence of metastases. Generally, it is said that the LS case to be limited to the lymph nodes near the lung and lung tumors one. If you have cancer spread beyond it, the ES is said.
In the case (in many cases, including paclitaxel cyclophosphamide, cisplatin, doxorubicin, etoposide, vincristine and / or) of LS-SCLC, combination therapy, I was administered together (RT) and concurrent thoracic radiotherapy.
Improving the survival rate of LS-SCLC has been shown to chest RT. Between 75% of people indicating the (CR) “complete remission” and 45% initial objective response rate very high between the observed using the LS-small cell lung cancer chemotherapy 90% from 60% ( It is defined as the disappearance of radiological evidence of clinical and all RR), of a tumor. Unfortunately, recurrence is the rule, the median survival is 24 months from 18 months. Under most circumstances, has spread widely in the natural history of the tumor at a very early stage, to respond dramatically in almost all cases, SCLC is or RT / CT, the role of little for surgery in 1970 this disease It is from the year. However , when it is used before chemotherapy, in the case of (“very limited”) small asymptomatic, node-negative SCLC-san, recent studies, a surgical resection This suggests that to improve survival. (“Adjuvant”).
The ES-SCLC, the combination chemotherapy, the standard treatment of radiation therapy, if temporary, shortness of breath, such as have faster than normal, and pain caused by bone metastases and liver, SCLC is for the treatment of brain metastases responses to whole brain radiation therapy were added only to alleviate symptoms such as. Combination therapy is composed of cisplatin, cyclophosphamide, vincristine and carboplatin and, from a variety of agents. 30% of patients had a complete response to combination chemotherapy and 15%, response rate is also high for a wide range of disease among the majority of response objective of at least some. However, in many cases, the response of ES-SCLC short time. If it occurs in the target having a small cell lung cancer complete response to chemotherapy, (PCI), is used to prevent the development of brain metastases often prophylactic cranial irradiation after. This treatment is very effective, but it can cause fatigue and hair loss. Adverse effect was not observed at all in the prospective randomized trial with 2 year follow-up neurocognitive almost. A meta-analysis of the PCI confirmation randomized trial, it provides a significant advantage for survival. Finally, small cells are very sensitive to radiation therapy and chemotherapy, platinum-containing agents, in particular, basic circuit. However, most people with median survival and disease relapse remains low.