|Product name||Skin cancer-normal|
|No. of samples||49|
|No. of patients||47|
|Core diameter||2.0 mm|
|Section thickness||4 micrometer|
|Description||Skin cancer: 40 cases
normal : 9 cases
Product Related Literature
They occur (skin lesions) skin cancer, it is named after the type of skin cell from there. Derived from the underlying basal cell carcinoma, epidermal, the most common skin cancer, but is low risk. It is common and a lot, derived from the intermediate layer, but is easily spread if left untreated, squamous cell carcinoma, can be fatal. Melanoma pigment-producing cell is (melanocytes) is the most common, but with the highest positive, is spread more likely, and if not treated, it is that you can be fatal. Most cases are caused by an excess of to ultraviolet rays from the sun or tanning bed. Usually, the treatment is to surgically removed. Melanoma is one of the highest survival rates of cancer and more than 75% of the people who survived 10 years in the UK during the 2007-2005 period. In the UK, 12,818 people are diagnosed with malignant melanoma in 2010, about 10 million people, was diagnosed with non-melanoma skin cancer. 2746 deaths from skin cancer, there was a malignant melanoma of the 546 and 2203 of non-malignant melanoma. In 2008, 59,695 people are diagnosed with melanoma, 8623 people died in it in the United States.
Basal cell carcinoma present sun exposed parts of the skin, especially the face. It does not cause death rare they do not transition rarely. They can be treated with radiation therapy or surgery easier. Squamous cell carcinoma (SCC) is a common, than basal cell cancer much more frequently. They metastasize more frequently BCC. Even then, with the exception of lips, ears, and the transition rate of the SCC in immunosuppressed patients, it was very low. Melanoma is the most common of the three forms of skin cancer. there is a possibility that they will transition often, once they spread, lead to death.
Skin cancer angiosarcoma Paget’s disease dermatofibrosarcoma protuberans, Merkel cell carcinoma, Kaposi’s sarcoma, keratoacanthoma, spindle mast cell tumor, cancer, cystic adnexal carcinoma, breast, atypical fibroxanthoma, and leimyosarcoma less common I include. In BCC SCCS, in many cases, it indicates that it is caused by UV-B radiation through direct damage to DNA, these types of cancer is solely the UV-mutation. However, malignant melanoma, is caused by the radiation through the DNA damage damage.The indirect DNA indirect caused by reactive oxygen species and UV-free radical mainly. The study, in combination with exposure of 60 minutes, the result has not been used in very small amounts to an increase of free radicals in the skin, the absorption of three sunscreen component of the skin, the indicated time rarely ultraviolet are. However, the researchers, the new cream often contain specific compounds thereof, the combination of other components, tends to retain the compound on the skin surface. In addition, re-administration is added to reduce often the risk of the formation of radicals.
There are a variety of different symptoms of skin cancer. These, are included, the change of the number of moles of existing and skin, changes in skin No, the discoloration that you heal ulcering the skin, such as jagged expansion of mall and shopping mall. Basal cell carcinoma presents as a bump on the skin exposed to sunlight usually, procurement smooth, shoulder head, neck and pearly. Sometimes, small blood vessels can be observed in tumors. Bleeding and scab is developing often in the center of the tumor. It is wrong for pain that do not heal often. This form of skin cancer is the most deadly, it is possible without scarring often with the appropriate treatment, to remove completely. In many cases, the patch was thickened red, scaly, the sun, squamous cell carcinoma, the exposed skin. Some of these are hard dome, shaped like keratoacanthomas and hard nodules. There is a possibility that bleeding and ulcers may occur.
If SCC is not treated, it can develop into a large mass. Squamous cell carcinoma is a skin cancer the second most common. It is not as dangerous as melanoma but dangerous. Most melanoma is a brown lesion looking for black. Unfortunately, they are called amelanotic malignant melanoma, pink, melanoma of some, is fleshy and red color. They tend to be more aggressive. Signs of malignant melanoma, including changes in the elevation size of the mole, shapes, and colors. Or adult, Other symptoms, is the appearance of a new mole new pain, itching, bleeding and ulcers in. Mnemonic often used 6 mm D = “diameter” big “ABCDE” (more = asymmetry, B = “border” “coast of Maine sign” (irregular update =), C = “color” is a (Variegated) – size of the eraser), “Evolution” = E is.
Squamous cell carcinoma is a malignant epithelial tumor derived from the field of squamous epithelium of mucous membranes or skin and flat. Often, it is also possible that elevated fungating for, to repeat in the ulcer border or irregular. The macroscopic tumors under the microscope, to destroy or sheets basement membrane and tumor cells, so as to form a compact mass that enters the (dermis) binding the underlying tissue. In differentiated carcinoma, tumor cells are atypical / polymorphic, but it is similar to normal keratinocytes (abundant eosinophilic (pink) cytoplasm and a central nucleus, polygon, large) spinous layer from. , Immature / basal cells surrounding the mature from the center of the tumor mass: it tends to its position similar to that of normal epidermis. It is possible to convert a form fitting and squamous keratinocytes has a stacked concentric circular known as “epithelial keratin pearls /” or “well” tumor cells. Stroma surrounding is reduced, I will contain the inflammatory infiltrate in (lymphocytes). The poorly differentiated squamous cell carcinoma cells, keratinization and polymorphism are included more.
Sunscreen is effective, it is advisable to prevent squamous cell carcinoma and melanoma. There is little evidence that it is effective in prevention of basal cell carcinoma. Will include other tips to reduce the incidence of skin cancer: wear, protective clothing to avoid sunburning, a hat and goggles, to try to avoid the period of maximum exposure or exposure to the sun. U.S. Preventive Services Task Force, we recommend that it is advisable to avoid ultraviolet people between the age of 25 from 9 years old. Through a number of measures, including the following, will be able to reduce the risk of developing skin cancer,: to reduce the increase mid-day sun exposure and indoor tanning, use sunscreen, avoid the use of tobacco. There is insufficient evidence for or to screen for skin cancer. To be effective in prevention has been found that antioxidant supplements and vitamins. Data on the benefits of nutrition measures are temporary.