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Benign prostatic hyperplasia also, (BPH) is, and called benign hypertrophy (operation technical inaccuracies) benign prostatic hyperplasia prostate (BEP), and adenofibromyomatous hyperplasia, it is to increase the size of the prostate. BPH, prostate, formation of distinct nodes periurethral area larger, as a result, prostatic stroma and including hyperplasia of epithelial cells. Enough nodes, when compressing the urethra, of interfering with the normal flow of urine, part, the urethral canal to cause obstruction substantially complete at times. This is so that either contribute to this increased risk symptoms of urinary hesitation, urinary frequency, urinary tract infection, or urinary retention, and cause insomnia. infections urinary volume and body prostate-specific antigen level is increased due to inflammation caused, may be elevated in these patients, but do lead to cancer, BPH does not increase the risk of cancer . (The increase in the size of individual cells) hypertrophy, even in many cases, of the urologist, the two terms are used interchangeably, not (increase in cell number) BPH wind hyperplasia. I have considered the growth of prostate adenoma is to begin in about 30. About 50% of men have histologic evidence of BPH in 50, 75% 80 years, 40-50% of these men, the BPH, is important clinically.

Symptoms of BPH are classified as urination or storage. Symptoms of storage is included (nocturia) that you urinate at night (need convincing to void that can not be postponed) urinary frequency, urgency, and urge incontinence.(Waiting a stream starting) urine flow oscillation (when the stream is started, and stopped periodically) intermittently, the tension void, urinary symptoms including dribbling. Urination pain and disability are not normally present. Was evaluated using (IPSS) questionnaire International Prostate Symptom Score is designed to urinary symptoms and these storage to assess the severity of BPH. The BPH, in particular, there is a progressive disease if you are left untreated. I empty the lead to stagnation of bacteria increase in risk of urinary tract infections and bladder residue incomplete. It is formed by crystallization of the salt of the bladder residual urine bladder stones. Retention referred to as acute or chronic, is another form of progression. It is that you can not acute urinary retention, disable while gradually increased in chronic urine residual urine volume, bladder expansion. This can lead to low blood pressure bladder. May lead to renal failure Finally, some patients suffering from chronic urinary retention, called condition and obstructive uropathy.

I think most experts to function as a tolerance (the hormone and testosterone) androgen. It is available to generate a BPH androgens, but it means that there must always directly trigger condition. This is supported by the fact that the age of castration boy that they develop BPH. On the other hand, application of exogenous testosterone is not associated with a significant increase in the risk of BPH symptoms. Metabolite (DHT), testosterone, is an important mediator of prostate growth [quote] dihydrotestosterone. By the action of two testosterone 5α-reductase enzyme, DHT was prepared in the prostate from the circulation. This enzyme therefore is localized mainly in stromal cells, these cells are the major site of synthesis of DHT.

DHT is able to act in an autocrine manner to paracrine distribution of epithelial cells near or stromal cells. In both cell types, DHT is a mitogenic for stromal cells and androgen receptor and epithelium, coupled to the signal of the nuclear transcription of growth factors. The DHT, it is 10 times stronger than testosterone as attenuation from late androgen receptor. Inhibitors of 5α-reductase such as finasteride such clinical observations are given to people with this condition, the importance of DHT, is supported by causing nodular hyperplasia. And reduce the volume of the prostate prostate thus significantly reduced, in many cases, processing for the directory 5α-reductase DHT content, symptoms of BPH.

Testosterone promotes the growth of prostate cancer cells, but relatively low serum testosterone levels are found in patients with BPH. In a small study, the influence of the level of testosterone and dihydrotestosterone in the prostate with less medical castration, suggesting that reduce the level of prostate hormone and heterogeneous serum.
There is some evidence that estrogen plays a role in the etiology of BPH, but not the local conversion of androgens, this effect is mediated primarily by direct effects of estrogen itself to estrogen in prostate tissue will be displayed. Level of significant androgen, caused a marked atrophy of the prostate reduction in biological research dog castration, and estrogen levels as it is left. Research seeking the connection between prostate hyperplasia of people, and serum estrogen levels is not as common.

In 2008, for example, Yigal gut. BPH has announced evidence that caused lead to an increase in local-level rise of testosterone to 100 times higher than the serum level and hydrostatic pressure, by the lack of seed venous drainage system. If it is confirmed, to explain why serum androgen level that does not have a big difference does not seem to correlate with BPH, this mechanism would give the exogenous testosterone. It is also important for treatment.

In a microscopic level, BPH, 70 years of age or around the world, as they age, it can be seen by the majority of men in particular. However, clinically significant, symptomatic BPH rate depends on the way of life dramatically. Man to lead the lifestyle of the West, have a higher incidence of much of symptomatic BPH than men to lead a rural lifestyle and traditional. While has a huge incidence of this condition, is still under it men living in the city to adopt the lifestyle of the West, in rural areas, this is a very low level of clinical BPH men The interest in the West is confirmed by studies in Chinese indicating that you have.