|Product name||Normal endometrium|
|No. of samples||59|
|No. of patients||59|
|Core diameter||2.0 mm|
|Section thickness||4 micrometer|
Product Related Literature
The endometrium is the lining of the inside of the uterus of a mammal. To maintain the patency of the uterine cavity, thereby preventing adhesions between the opposed walls of the myometrium, endometrium, function and gland innermost layer of the lining for the uterus. During the estrous cycle and menstrual cycle, blood vessel-rich, the thickness of the endometrium, grows in glandular tissue layer. This represents the optimal environment for implantation of blastocyst on arrival in the uterus. (Detectable using ultrasound scanners) echoes, the central, endometrium, has an average thickness of 6.7 mm. During pregnancy, blood vessels and glands increase further the endometrium in size and number. Become space of the vessel is fused and are interconnected to form the placenta by supplying oxygen and nutrients to the fetus and embryo.
Endometrial lining undergoes cyclic regeneration. Most other mammals while subject to the estrous cycle, great apes and humans, displays the menstrual cycle. In both cases, first, the endometrium, to grow under the influence of estrogen. Ovulation occurs, however, once, in addition to estrogen, also ovaries begin to produce progesterone. This will change the growth pattern of the endometrial lining in the secretion. In the end, the lining of secretion, it provides an environment of hospitality for blastocyst of one or more. If you implant the blastocyst, lining remains as decidua. Fall off, become part of the placenta, it provides protection and support for pregnancy.
If inadequate stimulation attributed lining exists in the lack of the hormone, the endometrium is thin, remains inactive. In humans, amenorrhea, or it occurs in the absence of menstrual period. Postmenopausal lining is described as being atrophy often. There is without contrast, endometrium exposed to chronic estrogen, progesterone, resulting in hyperplasia. Further long-term use of oral contraceptive progestins very powerful, it is possible to induce atrophy of the endometrium. In humans, to build the lining of the endometrium, the average duration of the 28-day period of the sink. The endometrium, we are developing at different rates in a variety of mammals. Its formation is influenced by other factors season, climate, and stress at times. I will generate a certain hormone at various points endometrial itself along the cycle. This will affect the other parts of the reproductive system.
Endometrium is made up of a single layer of columnar epithelium resting on a layer of connective tissue that varies in thickness according to the impact stroma, the hormone. Base of stroma carry a rich blood supply of spiral artery to reach from the endometrial surface also uterine gland of cylindrical simple. In women of reproductive age, it is possible to distinguish between the two layers of the endometrium. In the lining of the fallopian tube instead of the two layers, I will only occur in the endometrium lining the lumen of the uterus. The functional layer is adjacent to the uterine cavity.
This layer is built after menstruation has finished the first part of the menstrual cycle the last. It is induced by (follicular phase of the menstrual cycle) estrogen, changes in this layer is caused by progestrone from the corpus luteum (luteal phase) later growth. It is adapted to provide an optimal environment for the growth and implantation of the embryo. This layer is shed during menstruation completely. The base layer adjacent to the functional layer and lower myometrium, to flow at any time during the menstrual cycle, the functional layer may not be developed therefrom. In the absence of progesterone, the arteries supplying blood to the functional layer, so bring menstruation, dying cells in that tier is to ischemia, contraction.
Hormone therapy induces the like of histological changes in the endometrium. Histologic patterns encountered in hormone regimen most commonly used is described. Oral contraceptives is associated with interstitial edema and pseudosecretory gland inactive, or atrophy,, decidual reaction without spiral artery, between quality granules. The progesterone of high potency, there is a possibility that stromal marked, to induce nodule interstitial fibroids and vascular hyperplasia. To accelerate the maturity of the stroma, in many cases, ovulation induction therapy is associated with a mismatch between edema and glandular secretion indicating the change of initial, of decidualized stroma. Hormone replacement therapy is able to stimulate the proliferation of the endometrium to produce tumors and endometrial hyperplasia when using estrogen alone.
If the progesterone regimen and estrogen are used, may be found in various combinations is a wide range of histological pattern: secretory endometrium growth and endometrial, adenomatous hyperplasia and adenocarcinoma, stromal atrophy any of the above decidua and conversion hyperplasia, glandular metaplasia, and atrophic endometrium. Progesterone therapy can be seen in progesterone therapy sometime after squamoid is in the membrane in the uterus “morules.” Is followed by changes in the secretory endometrium, nuclear vacuoles, and decidua reaction, mainly because of the tumor and endometrial hyperplasia changes in the secretion do not rule out residual cancer. The hormone therapy for breast cancer, tamoxifen, act as estrogen agonists of the endometrium on to work as an anti-estrogen in breast cancer is high, endometrial hyperplasia, polyps, adenomyosis, tamoxifen therapy adenomatous hyperplasia , and may be associated with adenocarcinoma.