|Product name||Non-neoplastic liver (matching CS)|
|No. of samples||59|
|No. of patients||59|
|Core diameter||2.0 mm|
|Section thickness||4 micrometer|
Product Related Literature
Non-neoplastic liver , the huge amount of information published on this issue recently, it is part of the classification and nomenclature classic non-neoplastic nodular lesions and tumors of the liver. Be surgically removed, autopsy liver detects terms Born Ken current liver damage, diagnostic histopathology of nodular non-neoplastic (tumor like). It is a rare sample routine liver in general, these units and even rare.
Focal nodular hyperplasia, nodular regenerative hyperplasia, compensatory hyperplasia of the liver, including a clear pseudonodule liver from angiography part nodule conversion focus fatty change, node of non-neoplastic changes angiography nodular liver area purpura nodular lesions and leaf, pseudolipoma, of the liver, such as fake lymphoma atypical, oxygen-free pseudolobular necrosis, intrahepatic bile duct adenoma, tumor malpractice of interlobular and bile duct, and inflammatory pseudotumor is indicated by cirrhosis large regeneration node variable, and so lonely node necrosis,. While was observed at a similar rate in a variable hardness liver cirrhosis and non, some of them, the other was developed mainly liver cirrhosis or variable hardness non. Some self-generated and other irregular reflection or multiply. With regard to the pathogenesis of these units, that it plays a role in order to concentrate hormonal imbalance and hepatic circulation of abnormal hyperplasia, cancer characteristics before, abnormal metabolic disorders, necrobiotic or malpractice, the infection process is assumed will be. Knowledge and understanding of non-neoplastic nodular lesions of these is required for the differentiation and accurate diagnosis of nodular lesions from these neoplastic liver nodules.
Observed in the winter flounder like a non-neoplastic liver lesions and tumors Boston Harbor, from Massachusetts, Pseudopleuronectes americanus,. Pancreatitis cholangiitis of inflammatory lesions, pericholangiitis, pericholangial fibrosis, and hepatitis. Necrotic lesions are composed of vacuolated cell lesions of unique liver parenchyma and focal coagulation necrosis mainly. Hypertrophy and proliferative lesion macrophage aggregate hyperplasia and a number of the most prominent. Pre-cancerous lesions of hepatocellular adenoma and changes in cell basophilic lesions mainly. Varieties hepatoma morphological some cancer, including undifferentiated adenocarcinoma and cholangiocarcinoma. The pathogenesis of lesions observed from the perspective resistant hepatocyte model of liver and chemical contamination artificially introduced. This study, with respect to bioaccumulation potential of the chemical pollution of other people, of edible tissue from further evaluation especially food endemic neoplastic disease warrants bottom-living fish.
To xenobiotic-induced liver tumors in fish collected from natural water in a logical role of profit increase public overall surrounding the topic of cancer media attention of many fish, and as an environmental sentinel of aquatic toxicity due is given. There is strong evidence, however, the fish should be recognized as a worthy model for non-neoplastic liver toxicity in terms of research in the laboratory and field. For biochemical analysis, is not typically used to evaluate the damage (as opposed to mammals) fish liver regularly histopathological evaluation, the extent or presence of non-tumor liver toxicity It is required to determine.
It is required to identify and unfamiliar these animals and interpret subtle changes in the liver, the pathology of many mammals may be uncomfortable. Difference between mammals and fish, this is, that the biochemical properties and physiological, to note and that there is a similarity than pathological response is peace of mind in terms of microscopic anatomy macros and those of liver toxic substance I can. For mammals, and co-factors, such as nutrition and disease co-infections such as the presence of human lesions or indefinite, structural, interpretation and recognition of changes in the liver of fish of functional diversity that exists between the different species There can be complicated by a set.
A method that can predict autopsy fish liver, metabolic capacity, and anatomical considerations, exposure to toxins, estimated physiological comprising comparison the microscopic appearance of the black of mammals, : This is a form of xenobiotic toxic compounds that are underlined in some of the basic data types found in the case of liver toxicity test fish and most often the liver and is divided into several areas, including the easily I adopt the histological response, detoxification or removal of poisoning, and the response of the liver specific hepatotoxins last fish.
Considerations and physiological anatomy of the above, if you look at the way that affects the liver of fish from the morphological point of view, we, response of the liver of the fish to mammals to toxic exposure we Please see that there is a tendency to weight reduction compared. The high concentration of toxic Another way to state this is the observation that needed to cause similar changes in the liver of fish. Some of the factors described above, the relative tolerance of fish hepatotoxins is possible that due to the uniform distribution of the biotransforming enzyme perfusion rate of fish liver is so low to limit the exposure of toxic basement membrane of liver cells such fact that the resistance and non-induced easily several enzymes. The toxic damage distribution after exposure, another trend in the liver of fish is that without a strip pattern that is common to the sub-lethal poisoning in a mammal, that there tends to be random. Again, this feature, the uniform distribution of the biotransforming is given the fact the architecture of strip and enzymes in the liver of a fish is not clear.