Nasal cavity olfactory neuroblastoma

Product name Nasal cavity olfactory neuroblastoma
Cat. No. 2195223A
No. of samples 1
Description nasal cavity, olfactory neuroblastoma
Age/Sex : 26/M
Price 197 EUR
260 USD
170 GBP

Nasal cavity olfactory neuroblastom

Product Related Literature

Neuroblastoma (NB), about 50 cases of hundred six years in the United States is a neuroblastoma almost half, and one hundred cases of annual incidence per year, in the most common cancer in childhood and infancy in the UK In case of children under the age of 2 is a extracranial solid cancer the most common. This is a neuroendocrine tumor arising from neural crest element of the sympathetic nervous system of (SNS). This comes from one of the adrenal glands most often, but it can occur with pelvic nerve tissue neck, chest, or abdomen.Neuroblastoma is one of the human malignant tumors some that show spontaneous regression of the undifferentiated state in the cell types of benign completely known. Low, intermediate and high risk: This is a disease divided shows the extreme heterogeneity, the three categories of risk. Be treated successfully with the available multi-modal therapy most intensive whereas difficult, there is a disease of high-risk, low-risk disease, good results and infants that is common to surgery or observation only in it is most common. In addition, nasal neuroblastoma known as olfactory neuroblastoma, is considered classified as olfactory epithelium to occur because there is room for discussion. However, intranasal neuroblastoma, not to be confused with neuroblastoma If it is clinically different entities is not a malignant tumor of the sympathetic nervous system it.

What kind of symptoms are apparent, 50-60% of all cases, before exhibiting the metastatic neuroblastoma, neuroblastoma has spread to other parts of the body often.
The most common site of neuroblastoma (ie, primary tumor) derived from, it is adrenal glands. 40% of the tumor localized This occurs in 60% of cases of disease and a wide range of. Neuroblastoma, sympathetic nervous system, gate – can occur anywhere along the circuit of the hip joint. frequency of different parts, including breast door (1%), (19%), or stomach (30% non-adrenal) pelvis (1%). In rare cases, it is not possible primary tumor of interest. It is rare, but diarrhea treatment-resistant cross myelopathy (tumor spinal cord compression, 5% of cases), (secretion of tumor vasoactive intestinal peptide, 4% of cases), Horner’s syndrome presentation distinctive, (cervical and renal artery compression and secretion of (catecholamines, (paraneoplastic claim reason, 1.3% of cases), 1.3 percent of high blood pressure cases ataxia and eye claw Taunus myoclonus syndrome include tumor section, 2.4%) of the time).

The etiology of neuroblastoma is not well understood. Most cases are sporadic, it is non-families. About 1-2% of cases in the family has been associated with gene specific mutation. Familial neuroblastoma in some cases due to germline mutations in (ALK) gene rare anaplastic lymphoma kinase. Germline mutation in the gene or KIF1B PHOX2A is involved in familial neuroblastoma as well. Neuroblastoma, Beckwith and neurofibromatosis type 1 – is a function of the Wiedemann syndrome. Oncogene amplification of N-Myc in the tumor is a general knowledge in neuroblastoma. – 10 or 100 times – to 300-fold or 3: The degree of amplification shows the bimodal distribution. The presence of this mutation is strongly associated with advanced stages of the disease.

The gene segments LMO1 Duplicates in neuroblastoma tumor cells, increasing the risk of developing malignant cancers was shown. Neuroblastoma, and is connected to a change in the copy number within NBPF10 gene that results in the 1q21.1 1q21.1 duplication syndrome or deletion syndrome. Risk factors Several have been proposed, it has been the subject of ongoing research. Many studies due to the early onset characteristics, focusing on the factors of parents and pregnant around the pregnancy. (ie exposure to chemicals in a particular industry) occupation factors are included, we examined the factors of birth with the use of drug smoking, alcohol consumption, during pregnancy, but it was inconclusive results. Other studies, consider a possible link with exposure to infectious diseases and atopy in life early, I use the use of mother of hair dye and fertility drugs and hormones.