|Product name||Kidney renal cell carcinoma|
|No. of samples||1|
|Description||kidney, renal cell carcinoma
Age/Sex : 62/F
Product Related Literature
Clear cell renal papillary carcinoma, cancer of the kidney known as clear cell tubular papillary renal cell carcinoma and even abbreviated the CCPRCC, have a microscopic morphological features papillary renal cell carcinoma, clear cell kidney cancer It is the type that has been described recently, immunohistochemistry and molecular changes is important pathologically based on it. In other words, the core to have a nuclear cusp is in close proximity to the aspect of the lumen CCPRCC classic. typical structure of the gland most basally located nucleus, that is, the cytoplasm in the immediate vicinity of the basement membrane.
(Known as adrenal also RCC,) renal cell carcinoma, it is derived from kidney cancer in the lining of the renal tubules of the nearest, to kidney very transport of GF glomeruli descending part of the nephron small tube (glomerular filtration). Accounted for about 80% of cases, RCC is the most common type of kidney cancer in adults. This is described as one of the most lethal of cancers urological all. Is a partial nephrectomy or radical most commonly, initial treatment remains of the pillars of health care. Tumor is limited to the renal parenchyma, the 5-year survival rate is 60-70%, but this was significantly reduced, wherein the transition is spreading. This is the response of some cases of immunotherapy, but there are relatively resistant to chemotherapy and radiation. Targeted therapy sunitinib, temsirolimus, bevacizumab, and sorafenib and interferon-α, such as this has improved the outlook for RCC.
Daniel Zeneru Prefecture, the first reference, suggested a tumor that occurs in the kidney in the text Practicae Medicinae, which was announced in 1613 first. Miril has announced a clear case of early renal cell carcinoma in 1810. In April 1809, he suggests that it is in the later stages of pregnancy, and describes the case presentable Francoise quiet to City Hospital of Brest on the 6th, the 35-year-old woman. Koenig has announced the initial classification of renal tumors based on the macroscopic form in 1826. Koenig Split medulla form scirrhous tumor, steatomatous, and fungi.
After classification of tumors, researchers have attempted to identify the tissue of origin of the renal cell carcinoma. Pathogenesis of renal epithelial tumors, one of contradiction most enduring of surgical pathology modern provided. Discussion in 1883, he was started by Paul announced Gras Witz, small, his observations of morphological yellow kidney tumor. Grawitz has entered into a lung tumor only those of adrenal origin papillary tumor, whereas renal tissue of. 1893, Poruzudekku atrophy, published a description of the renal tumor have mentioned some atypical features prominent gradient of atypical features of these between the malignant tumor that he and the adjacent tubule and tubule I challenge the assumption that theory by Grawitz with. Support in 1894 Otto Lubarsch,, assumptions theory coined by Grawitz long-term hypernephroid tumor, which was revised in adrenal of Felix Victor Birch-Hirschfeld to describe these tumors. It is considered the origin of the adrenal gland of renal tumor, sharp criticism Grawitz offer has not been proven in Stoerk Oscar in 1908. In spite of the argument convincing to assume that theory by Grawitz, adrenal related connotation and long-term adrenal continued in the literature.
Such as foot and Humphries, and foot. And coined the term single cell cancer renal stress in renal tubular origin of these tumors. Their names will be changed to long-term renal cell carcinoma widely accepted already Fetter little. Conclusive evidence to resolve any dispute has been proposed by Oberling et al. 1959, people who have studied the fine structure of clear cell renal cell carcinoma 8. The cytoplasm of tumor cells, they found that deposits and mitochondria contain a lot of fat and glycogen. They identified the cell membrane which is arranged perpendicular to the membrane cells and occasional containing microvilli in free coverage. They are characteristic of these tumors was concluded that indicate that arise from epithelial cells settling and renal tubular any of the issues discussed in tumor pathology finally determined by it.
Historically, doctors expect the person to submit what is known as a classic triad of symptoms. 1 hematuria is when there is blood in the urine contains: this triad of symptoms. 2 abdominal pain is a pain in the side of the body between the ribs and femur. It is similar to three abdominal mass, and fullness, but big. That this triad classic symptoms of current only occurs in 10-15% cases are known, which may indicate renal cell carcinoma (RCC) in the advanced stages. Today, (mostly means that there is no symptom) is a fairly asymptomatic, people are detected in a test accident for other diseases usually RCC.