|Product name||Colon and rectum cancer|
|No. of samples||59|
|No. of patients||59|
|Core diameter||2.0 mm|
|Section thickness||4 micrometer|
Product Related Literature
In addition, in colon cancer known as cancer or colon cancer of the colon, cancer, are in addition to uncontrolled growth of cells in the colon or rectum or is (colon). The genetic analysis of colorectal tumor essentially, the same genetically, indicating that it is a cancer. Typically, symptoms of colorectal cancer, would include rectal bleeding that is associated with changes in bowel habits and weight loss, sometimes anemia.
As a fraction of the cases hereditary disease underlying are involved, colon most cancers can be attributed to age and lifestyle. Usually begins in the intestinal mucosa, and if not treated, the lower, which in turn can be converted into the muscular layer through the intestinal wall. Screening and is effective in reducing the risk of death from colon cancer, it is recommended starting at age 50, people will continue until 75 years old. Usually, colon cancer, which is localized be diagnosed by colonoscopy or S-shaped colonoscopy.
Cancer in the wall of the intestine, while the cancer has spread widely in the body, curing is not cured typically often surgically, control, attention to the durability of the human using chemotherapy then , I have improved the quality of life. Colorectal cancer is a cancer that is most frequently diagnosed in the three largest in the world, but the developed countries is common it. About 60% of cases are diagnosed in developed countries. It is estimated that that all over the world in 2008, new cases of 1.23 million of colon cancer will be diagnosed clinically, it killed 608 million people.
Symptoms and signs of colon cancer is dependent on the position of the colon tumor whether it has spread to other parts of the body (the transition). Traditional signs include: worsening of constipation, blood in feces, reduction of gauge stool, loss of appetite, weight loss, and anyone over the age of 50 nausea and vomiting. Anemia and rectal bleeding is a function of high risk in patients over 50 years of age, but symptoms including weight loss and a change in bowel habits, it was generally described other is related only usually if bleeding.
Genetic risk will occur with little or no greater than 95 percent from 75 of colon cancer in humans. About 10 percent of cases are older age, male sex, high-fat, red meat and alcohol, obesity, smoking, and lack of exercise is associated with insufficient activity other risk factors. I see more than one drink will increase day by day the risk of alcohol.
People with (ulcerative colitis and Crohn’s disease) and inflammatory bowel disease, the risk of colon cancer is high. Long human risk is greater than had worsening severity of inflammation and disease. It is recommended for prevention and high-risk group of these in colonoscopy and regular aspirin. People with inflammatory bowel disease, accounting for less than 2% of colon cancer cases every year. 2% is a colorectal cancer 8% in ’10 after 20 years in those with Crohn’s disease, 18% after 30 years. About 16 percent of developing colon cancer or precursor cancer and after 30 years in those with ulcerative colitis.
Those having a family history of primary more than two, the risk of increased two to three times the disease, which will be explained about 20% of the group of all cases. Number of genetic syndrome is associated with rate of colon cancer in high. Familial adenomatous polyposis and Gardner’s syndrome in the (FAP), most commonly, hereditary nonpolyposis it is present in about 3% of persons with colorectal cancer.Other syndrome strongly associated in these It almost always happens, the cancer is (Lynch syndrome or HNPCC) colon cancer, cause 1% of cases.
Most of the deaths from colorectal cancer that is associated with metastatic disease. Transition associated with cancer Colon, one – the gene that appears to contribute to the likelihood of metastatic disease, I was isolated. This is a transcription factor that affects the expression of hepatocyte growth factor. This gene is linked to a distributed invasion of colon cancer in metastasis and tumor growth in mice and cell cultures, and distribution. It is also associated with response to treatment.
Change of genetic variation of colon cancer general are also much more epigenetic changes. And others Vogel is as described, (together referred to as “driver mutations”) in, 1-5 tumor suppressor mutation with a mutation “passenger” and about 60 extra carcinogenic mutations in one or two only average colon cancer some. It has been well-studied tumor suppressor genes and oncogenes, will be described in the pathogenesis.