|Product name||Colon adenocarcinoma metastasis|
|No. of samples||1|
|Description||colon adenocarcinoma metastasis
Age/Sex : 41/F
Product Related Literature
In metastatic disease or metastasis, is the spread of cancer to some non-adjacent organ or another organ or a portion of one. Was thought to be capable of infection or malignant tumor cells to metastasize formerly (abbreviated Mets) transition is generated in this way, a new instance of the disease is called, but since it is, further research is revised will be. Home transition is a Greek word meaning στάσις, stagnation, “accommodation” μετά, and, “Next”, “deviation” from the meta. Plural form is a transition.
Cancer can occur in the cells of the damaged cells genetically gradually be generated by proliferation unorganized controlled. The non-proliferation this control, cell division generates the primary tumor. Cell is a tumor undergoes metaplasia anaplaziya is followed by the results of the malignant phenotype, finally dysplasia. Extravasation of the position of the second for tumor formation is followed, this allows the blood vessels of malignant phenotype in blood circulation.
After that they move through the (circulating tumor cells) blood flow to the tissue and other parts of the body is possible, some cancer cells may acquire the ability to penetrate the vessel wall and lymph / or. This process is known (respectively), such as lymph or hematogeneous rating as well. When the tumor cells come to rest in other places, they continue to re-enter multiplying the walls and blood vessels, thereby forming a detection tumors clinically different in the end. This new tumor is also known as a tumor (or secondary) metastatic. Transition is one of three features of malignancy (contrast benign tumors). Varying degrees (e.g., basal cell carcinoma is not transferred almost) is most tumors, and metastasis.
When cancer cells metastasize, the new tumor is called metastasis or secondary cancer, the cells are the same as the primary tumor. Breast cancer, with metastases to the lungs of the secondary tumors, for an example, instead of the abnormal cells in the breast, the unit is made from the lungs for abnormal cells. Thereafter, tumors of the lung is called metastatic breast cancer, not the lung. Cancer cells to leave the tumor site of the original shifted to other parts of the body via the blood, where metastasis, by direct or expansion, is a series of complex steps of the lymphatic system. To do so, malignant cells is connected to the break away from the primary tumor, separating the tumor from the surrounding tissue, and degradation of extracellular matrix (ECM), about the make-up protein. The proteolysis of these cancer cells can be destroyed and escape ECM. In the trend at a rate higher than expected from statistical randomness, spread to tissue or organ specific, the position of the transition is not a coincidence and different types of cancer always. Breast cancer, for example, tend to bone metastasis, the lungs. This feature, chemokines are thought to be mediated by soluble molecules signals, and converts the growth factor β such. By the action of a class of proteins known as metastasis filter dozen is known, the main body to resist the transfer by a variety of mechanisms.
Amoeboid movement and population mobility mesenchymal-type exercise: human cells have three types of exercise. Cancer cells switches the different movements often opportunistic. Either stop, by blocking the required several steps of the movement of both types of either or in some way at least, researchers some cancers, treatment can slow the spread of cancer I hope that you find. Review the conditions required for cancer metastasis, called tumor angiogenesis, researchers cancer found that one of the most important events are necessary for the growth of new vascular network. This, it is possible inhibitors of angiogenesis may prevent the occurrence of metastases were found.
There are different types of cells several essential for tumor growth. Specifically, endothelial progenitor cells, is very important for the growth of the cell population of tumor vessels. Along with the fact that endothelial progenitor cells that is important for angiogenesis and metastasis, this finding was published in the gene development and science magazine. The importance of endothelial progenitor cells in metastatic tumor growth, angiogenesis and was confirmed by the recent publication of cancer research. In this paper ingenious, that it can be labeled with inhibitor 1 DNA binding endothelial progenitor cells. This new discovery is that it also was able to monitor the endothelial progenitor cells from bone marrow into the blood of tumor stroma, researchers, it was incorporated into the tumor vasculature. This finding of endothelial progenitor cells involved in tumor vasculature, vascular development in metastatic tumors and security demonstrates the importance of this cell type. In addition, removal of endothelial progenitor cells in the bone marrow produces a significant decrease in vascular development and tumor growth. Thus, endothelial progenitor cells, is very important in a new therapeutic target of current and tumor biology. In the process of cell movement in the base of the molding transfer, NFAT transcription factors are involved in breast cancer in particular. Indeed, NFAT5 and NFAT2 are migratory birds in breast cancer and Puropuro invasive, it is an inhibitor of NFAT3 cell movement. Adjusting lipocalin 2 to increase the invasion of breast cancer cells, and regulates the expression of the ligand and TWEAKR, NFAT1 inhibits the NFAT3 lipocalin 2 expression slowed cell infiltration.
The liver, an important organ in animals and some other vertebrates are present. It has a wide range of functions, including detoxification, protein synthesis, and production of bio-chemical and necessary for digestion. It can be used in the short term new technologies liver dialysis, a method of compensating required for survival, the lack of long-term liver function, there is currently no liver. It plays an important role in metabolism, glycogen storage, disintegration of red blood cells, plasma protein synthesis, hormone production, and the body has a number of functions in the body, including detoxification. It is located below the diaphragm in the abdominal-pelvic region of the abdomen. It produces alkaline compound to help digestion by emulsifying bile, the lipid. Many of them, small is necessary for the normal function of life, organization highly specialized liver is to regulate a wide range of mass biochemical reactions such as decomposition and synthesis of complex molecules.