|Product name||Bladder transitional cell carcinoma|
|No. of samples||1|
|Description||bladder, transitional cell carcinoma
Age/Sex : 56/F
Product Related Literature
Usually, (UCC or urothelial cell carcinoma also TCC,) transitional cell carcinoma, is a kind of cancer that occurs in the urinary system: appendage kidney, and bladder,. This is the most common type of cancer of the urachal bladder cancer, ureter, and urethra. This is the most common type of second of kidney cancer, but it is 5 to 10 percent of the primary malignant renal tumor of all. TCC is derived from transitional cell lining, to the inner surface of the tissue hollow body like this. The term “urine” is used to refer specifically to mean TCC urinary tract, urothelial carcinoma. Urothelial cancer, is a classic example of a malignant tumor arising from the environment carcinogenic effects. Cause the most important by far is smoking that contribute to about half of the disease. Exposure, and that it predisposes to bladder cancer is known to pesticides such as those workers in the oil industry for the production of pigment and chemical dyes (prototypically aniline dye) was received. Interestingly, the risk is increased, urine, and thus is reduced by increased fluid consumption probably less surface urine “Rt is more”. On the contrary, such as long-haul truck drivers who happen once long-term urinary retention, risk increased between. As with most cell carcinoma, physical stimulus is associated with an increased risk of malignant transformation of the urothelium. Therefore, (as in patients with multiple sclerosis or paraplegia) urothelial cancer, chronic urinary tract stone disease, chronic catheters, and is more common in connection with chronic infection.
Transitional cell carcinoma (TCC) is, get to treatment is very difficult. Treatment of stage TCC localized is a surgical resection of the tumor, but frequently relapse. A regimen of six (this is the chemotherapy drug) was given mitomycin into the bladder, some patients, a single dose in a matter of weeks or postoperative period or immediate (24 hours), after the operation It is said. Early TCC / localized, can be treated with injection of BCG into the bladder. They are given weekly for three weeks (or induction course or) six weeks (maintenance / booster dose). Likely to develop systemic tuberculosis (TB) is low, become sensitized to BCG patient or cause serious intolerance, for scarring potential, side effects, reduce the volume of the bladder.
In surgical treatment patients fundamental in the form of being able to onset of muscle invasion, carried out in the gall bladder prostatectomy usually lymph node sampling. Because in such patients, bowel loop acts as a storage area for frequently to urine evacuation before or from the body through urostomy or urethra each or “neo-bladder”, and you can create “drug pipeline” it is used to. The TCC, including (methotrexate, vinblastine, adriamycin, cisplatin) to the MVAC chemotherapy regimen. Bladder cancer is one of several types of malignant tumors due (i.e., urothelium) to the bladder epithelium. In rare cases, the bladder is not configured in cancer of non-epithelial, such as sarcoma and lymphoma, but not included in the Common Name them normal “bladder cancer”. This is a disease that abnormal cells are applied to the outside of the control of the bladder. Store hollow, bladder is a muscular organ the urine, it is located in the pelvis. Summarizes the normal tissue structure urothelium, transitional cell carcinoma, precisely, the most common type of bladder cancer, known as urothelial carcinoma or more. In addition, it is estimated 383,000 cases of bladder cancer, the world exists. Bladder cancer, cause blood of normal urine (flushing). The blood in the urine can be detected by (microscopic hematuria) microscope or just seen naked eye (macroscopic / gross hematuria). Hematuria is the most common symptom of bladder cancer.
The symptoms of a possible other, there is a feeling to urinate without being able to do so pain during urination, urine, or frequency. It also, not specific to bladder cancer, signs and symptoms of these are caused by non-cancerous disease infection of the prostate, such as cystitis and overactive bladder. I thought hematuria, such as vascular malformation stones, infection, kidney disease, and kidney cancer, and the cause of many other of the urethra and bladder. Is a major factor for some cancers of the bladder, smoking in most populations, smoking is associated with more than half of all cases of bladder cancer in one third of cases of many men and women . There is a linear relationship between the risk and there smoking, non smoking reduces the risk. that passive smoking is included has not been proven. In a study of 10 years, including 48,000 people almost, men who drank 1.5 liters of water per day, the researchers one found that as compared with men who drank a significant reduction in the incidence of bladder cancer is small 240 ml per day (about 1 cup). This has not been confirmed in other studies still, part of the bladder cancer, the authors suggest might be due to the direct contact carcinogens bladder excreted in urine.
30% of bladder tumors, resulting from occupational exposure to carcinogens such as benzidine workplace such probably. 2 located in cigarette smoke – also naphthylamine, increasing the risk of bladder cancer has been shown. (Including the shoes) bus drivers, rubber workers, exercise mechanics, leather, blacksmith, machinery manufacturer, profession at risk are mechanics. We are the frequent exposure to permanent hair dye for beauty shop, and is considered to be at risk. It is considered mutations in HRAS, and KRAS2, RB1, FGFR3, that it may be associated in some cases.
In a study of 2008, and vegetables conclusion fruit, orange yellow, “fruits and vegetables specific, you can take action to reduce the risk of bladder cancer” carrot and especially the World Health Organization commissioned, those containing selenium is associated with a reduced risk of moderately bladder cancer probably. Cruciferous vegetables and citrus fruits, are identified as having a possible protective effect. However, analysis of 47 909 people in the medical field, in follow-up studies, as compared to a statistically significant decrease among those people that consume a large decrease in cancer, and yellow vegetables generally Fruits and particularly cruciferous vegetables that correlation was found mostly between the high consumption of green leafy vegetables and. The bladder is one of the most sensitive organs in the induction of detoxifying enzyme extract, but several studies have shown. This is evident in bladder cancer in vitro and in vivo human cells, in animal models. In human cells caused by bacteria sulforaphane potential in vitro anti-cancer effect bladder cancer, germ extract sulforaphane, broccoli was observed to induce cell cycle arrest and apoptosis.